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Testosterone and Vaginal Function by Elisa Maseroli; Linda Vignozzi is a Medicine article available to read on EtoBox.

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## Introduction: Androgens have been shown to exert beneficial effects on vaginal physiology, at least partially independent of their aromatization to estrogens. androgen deficiency in the vagina and in the other genitourinary tissues contributes to the development of vulvovaginal atrophy and genitourinary syndrome of menopause, resulting in impaired arousal and lubrication and dyspareunia. ## Objectives: To summarize the role of testosterone in modulating vaginal structure and function. ## Methods: A qualitative review of the relevant literature on the topic was performed using the pubmed database. we present a summary of preclinical and clinical evidence supporting the involvement of testosterone (t) in vaginal physiopathology and discuss it in terms of the role of the vagina in female sexual response. ## Results: Androgens are important in the differentiation of the vagina and in maintaining trophic and functional actions in postnatal life, as suggested by the detection of the androgen receptor and of the key enzymes involved in androgen synthesis. t is essential for the integrity of vaginal tissue structure (including non-vascular smooth muscle thickness and contractility and c

Who reads Testosterone and Vaginal Function?

Author

Elisa Maseroli; Linda Vignozzi

Publisher

Oxford University Press (OUP)

Published

2020

Language

EN

Field

Medicine (Health Sciences)