About this Medicine article
Bispectral analysis in trauma patients: An observational study by J.S. Holger; J.D. Fuerstenberg; S.K. O'Keefe is a Medicine article available to read on EtoBox.
nonhemorrhage controls. The MAP, lactate, and cumulative hemorrhage volume per 100 g of rat weight (CHV) were measured prehemorrhage and then every 15 minutes posthemorrhage for 120 minutes. Data were reported as mean6SEM. Group comparisons were analyzed by analysis of variance with repeated values; post hoc testing was by Bonferroni adjustment (all tests were 2-tailed, a=0.05). Results: Before hemorrhage, the ETOH1 and ETOH-were evenly matched for lactate and MAP. Ethanol levels at tail amputation were 170668 mg/dL. CHV (mL/ 100 g) were similar (P=.23) for the ETOH-(2.3660.24) and ETOH1 (1.8760.32) groups. No significant (P=1.00) difference was noted in posthemorrhage MAP between ETOH-(68.666.8 mmHg) and ETOH1 (69.367.2 mmHg) rats. The ETOH-group had a significantly (P\.032) higher lactate level (4.94 mmol/L61.07 mmol/L) than the ETOH1 group (2.27 mmol/L60.59 mmol/L). Conclusion: At this level of moderate ethanol intoxication, a lactic acidosis was not observed prehemorrhage. Posthemorrhage, ethanol intoxication may have ameliorated hemorrhagic shock, as evidenced by a lower level of arterial lactate.
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- Author
- J.S. Holger; J.D. Fuerstenberg; S.K. O'Keefe
- Publisher
- Elsevier Science; Elsevier ; Mosby Inc.; Elsevier BV (ISSN 1097-6760)
- Published
- 2004
- Language
- EN
- Field
- Medicine (Health Sciences)