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Retrospective analysis of non-anaplastic peripheral T-cell lymphoma in pediatric patients in Japan by Ryoji Kobayashi; Kazumi Yamato; Fumiko Tanaka; Yoshifumi Takashima; Hiroko Inada; Akira Kikuchi; Masa‐aki Kumagai; Shosuke Sunami; Atsuko Nakagawa; Reiji Fukano; Naoto Fujita; Tetsuo Mitsui; Masahito Tsurusawa; Tetsuya Mori is a Medicine article available to read on EtoBox.
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## Abstract ## Background Reports of non‐anaplastic peripheral T‐cell lymphoma (PTCL) in pediatric patients are relatively rare. ## Procedure We performed a retrospective analysis in patients with PTCL over an 18‐year period (1991–2008). ## Results We could analyze clinical data in 21 patients with non‐anaplastic PTCL; 10 were female and 10 male. Median age of onset was 11 years (range: 1–21 years). There were nine patients with PTCL, not otherwise specified (PTCL‐NOS); ten with extranodal NK/T‐cell lymphoma, nasal type; one with angioimmunoblastic T‐cell lymphoma; and one with subcutaneous panniculitis‐like T‐cell lymphoma. Initial lesions involved cervical lymph nodes in five patients, and the skin in five patients. In five patients, hemophagocytic syndrome (HPS) was the initial clinical feature. There were 12 patients with advanced stage disease (stages III and IV). Chemotherapy and radiation was administered in 18 and 2 patients, respectively. Among the two patients who did not receive chemotherapy and radiation, one patient died while being treated for HPS but another improved spontaneously. Although 5 patients relapsed, 18 of 21 patients remained alive without disease at last
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- Author
- Ryoji Kobayashi; Kazumi Yamato; Fumiko Tanaka; Yoshifumi Takashima; Hiroko Inada; Akira Kikuchi; Masa‐aki Kumagai; Shosuke Sunami; Atsuko Nakagawa; Reiji Fukano; Naoto Fujita; Tetsuo Mitsui; Masahito Tsurusawa; Tetsuya Mori
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1545-5009)
- Published
- 2009
- Language
- EN
- Field
- Medicine (Health Sciences)