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COPD patients hospitalized with exacerbations have greater cognitive impairment than patients hospitalized with decompensated heart failure by Mohani-Preet K Bajaj; Daniel R Burrage; Andrew Tappouni; James W Dodd; Paul W Jones; Emma H Baker is a Medicine article available to read on EtoBox.

What is COPD patients hospitalized with exacerbations have greater cognitive impairment than patients hospitalized with decompensated heart failure about?

## Purpose People with COPD have cognitive dysfunction, which is greater in those hospitalized for exacerbations than in stable outpatients. We tested the hypothesis that cognitive dysfunction at exacerbation is a disease-specific feature of COPD, rather than a nonspecific feature of hospitalization for acute illness, by comparing cognition between patients hospitalized for acute COPD exacerbations and those with worsening heart failure (HF). ## Patients and methods A total of 40 hospital inpatients were recruited, 20 patients with COPD exacerbations and 20 patients with congestive or left-sided HF. Exclusion criteria included previous stroke, known neurological disease, and marked alcohol excess. Participants completed the Montreal cognitive assessment (MoCA) and Hospital Anxiety and Depression Scale (HADS) and underwent spirometry and review of clinical records. ## Results Age (mean±SD, COPD 73±10; HF 76±11 years), acute illness severity (Acute Physiology and Chronic Health Evaluation [APACHE]-II, COPD 15.4±3.5; HF 15.9±3.0), comorbidities (Charlson index, COPD 1.3±1.9; HF 1.6±1.5), and educational background were similar between COPD and HF groups. MoCA total was significantly l

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Author
Mohani-Preet K Bajaj; Daniel R Burrage; Andrew Tappouni; James W Dodd; Paul W Jones; Emma H Baker
Published
2018
Language
EN
Field
Medicine (Health Sciences)

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