Opening book details…
Can I read Lactate, choline, and creatine levels measured by vitro ^1^H‐MRS as prognostic parameters in patients with non‐small‐cell lung cancer on EtoBox?
Lactate, choline, and creatine levels measured by vitro ^1^H‐MRS as prognostic parameters in patients with non‐small‐cell lung cancer by Hajime Yokota; Jianfei Guo; Munetaka Matoba; Kotaro Higashi; Hisao Tonami; Yosinobu Nagao is a Medicine article available to read on EtoBox.
What is Lactate, choline, and creatine levels measured by vitro ^1^H‐MRS as prognostic parameters in patients with non‐small‐cell lung cancer about?
## Abstract ## Purpose To determine the biochemical characteristics of lung cancer tissue using in vitro ^1^H‐MRS, and investigate the correlation between survival probabilities and lactate (Lac), creatine (Cr), and choline (Cho) concentrations measured by in vitro ^1^H‐MRS. ## Materials and Methods A total of 21 patients with lung cancer were included in this retrospective study. ^1^H‐MRS spectra measurements were performed at 6.35T using a JNM‐EX270, high‐resolution FT‐NMR spectrometer. ## Results When normal lung tissue was compared with lung cancer tissue, significant differences were noted most consistently in the levels of Lac and Cho, with lung cancer tissue showing higher values than normal lung tissue. Lac concentrations of lung cancer tissue were significantly higher in patients with recurrence compared to patients without recurrence (0.285 ± 0.096 μmol/g). The mean overall survival of patients in the low‐Lac group was 50.28 ± 6.47 months, which is significantly higher compared to the high‐Lac group, which had a mean survival time of only 30.49 ± 5.41 months. ## Conclusion Kaplan‐Meier analysis of the data showed that the overall and disease‐free survival probabilities we
Who reads Lactate, choline, and creatine levels measured by vitro ^1^H‐MRS as prognostic parameters in patients with non‐small‐cell lung cancer?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Hajime Yokota; Jianfei Guo; Munetaka Matoba; Kotaro Higashi; Hisao Tonami; Yosinobu Nagao
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1053-1807)
- Published
- 2007
- Language
- EN
- Field
- Medicine (Health Sciences)