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Prevalence, concordance and determinants of human papillomavirus infection among heterosexual partners in a rural region in central Mexico by Rocio Parada; Rosalba Morales; Anna R Giuliano; Aurelio Cruz; Xavier Castellsagué; Eduardo Lazcano-Ponce is a Medicine article available to read on EtoBox.
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## Abstract ## Background Although human papillomavirus (HPV) infection in heterosexual couples has been sparsely studied, it is relevant to understand disease burden and transmission mechanisms. The present study determined the prevalence and concordance of type-specific HPV infection as well as the determinants of infection in heterosexual couples in a rural area of Mexico. ## Methods A cross-sectional study was conducted in 504 clinically healthy heterosexual couples from four municipalities in the State of Mexico, Mexico. HPV testing was performed using biotinylated L1 consensus primers and reverse line blot in cervical samples from women and in genital samples from men. Thirty-seven HPV types were detected, including high-risk oncogenic types and low-risk types. Multivariate logistic regression models were utilized to evaluate factors associated with HPV. ## Results The prevalence of HPV infection was 20.5% in external male genitals and 13.7% in cervical samples. In 504 sexual couples participating in the study, concordance of HPV status was 79%; 34 partners (6.7%) were concurrently infected, and 21 out of 34 partners where both were HPV positive (61.8%) showed concordance for
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- Author
- Rocio Parada; Rosalba Morales; Anna R Giuliano; Aurelio Cruz; Xavier Castellsagué; Eduardo Lazcano-Ponce
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2001-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1471-2334)
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)