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Treatment of mild and severe cases of GERD by G. N. J. Tytgat is a Medicine article available to read on EtoBox.

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## Summary GERD prevalence continues to rise in contrast to peptic ulcer disease. The spectrum contains reflux esophagitis and so‐called `endoscopy‐negative GERD' or `non‐erosive GERD' (NERD) or S‐GERD and patients with `normal' overall 24‐h esophageal acidification but with a high `symptom‐index'. The majority of reflux patients will not need endoscopy initially. Prompt referral for endoscopy is indicated only if the patient has atypical symptoms or alarm symptoms such as dysphagia, anemia, weight loss, severe abdominal pain, or pain that does not respond to acid neutralization or suppression, or develops symptoms after the age of 50 years. Antireflux therapy consist of raising the head of the bed, maintaining normal weight, and avoidance of foods and drugs that precipitate symptoms, together with antacids or over‐the‐counter H~2~ receptor antagonists (H~2~RAs). If symptoms persist after these simple measures or if antacids or H~2~RAs are needed quite often, then a more formal first‐line treatment should be started. Many experts feel that a stepdown approach instead of a stepup approach is clinically and economically a more appropriate way of installing such first‐line therapy. Ph

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Author

G. N. J. Tytgat

Publisher

John Wiley and Sons; Blackwell Publishing; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley; Research Square (ISSN 0269-2813)

Published

2002

Language

EN

Field

Medicine (Health Sciences)