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This study investigates the expression of B-cell-activating factor (BAFF) and its receptors in multiple sclerosis (MS) patients compared to healthy controls. It finds that BAFF mRNA levels are elevated in MS patients, although BAFF protein levels in cerebrospinal fluid and plasma are similar across groups. Unique expression patterns of BAFF and its receptors are associated with different MS disease courses, suggesting a complex role of B cells in MS pathogenesis.

Author

scientificadda1992

Language

EN