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DNA Breaks from D-Penicillamine & Bucillamine by thayzaaires is a document available to read on EtoBox.

What is DNA Breaks from D-Penicillamine & Bucillamine about?

The study investigates the formation of DNA strand breaks in human lymphocytes induced by D-penicillamine and bucillamine, anti-rheumatic agents, in the presence of copper ions. The results indicate that these compounds lead to significant DNA damage, which is reversible and can be repaired within 8 to 24 hours, while also causing a decrease in cellular NAD levels. This DNA damage may play a role in the immunomodulating effects of these drugs, particularly in patients with rheumatoid arthritis.

Author

thayzaaires

Language

EN