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Comparative Evaluation of Galactomannan Test with Bronchoalveolar Lavage and Serum for the Diagnosis of Invasive Aspergillosis in Patients with Hematological Malignancies by Gupta, Ankit; Capoor, Malini R.; Shende, Trupti; Sharma, Bhawna; Mohindra, Ritin; Suri, Jagdish Chander; Gupta, Dipender Kumar is a Medicine article available to read on EtoBox.
What is Comparative Evaluation of Galactomannan Test with Bronchoalveolar Lavage and Serum for the Diagnosis of Invasive Aspergillosis in Patients with Hematological Malignancies about?
## Introduction: Invasive pulmonary aspergillosis (ipa) is a major cause of morbidity and mortality in patients with hematological malignancies. in recent years, testing for values of galactomannan (gm) in serum and bronchoalveolar lavage (bal) fluid has been investigated as a diagnostic test for ipa for such patients, but global experience and consensus on optical density (od) cutoffs, especially for bal galactomannan remains lacking. ## Methods: We performed a prospective case-control study to determine an optimal bal gm od cutoff for ipa in at-risk patients. cases were subjects with hematological diagnoses who met established revised definitions for proven or probable ipa established by the european organization for research and treatment of cancer/invasive fungal infections cooperative group (eortc/msg, 2008), without the use of bal gm results. exclusion criteria included the use of piperacillin/tazobactam and use of antifungals that were active against spp. before bronchoscopy. there were two control groups: patients with hematological diagnoses not meeting definitions for proven or probable ipa and patients with nonhematological diagnoses with no evidence of aspergillosis. fo
Who reads Comparative Evaluation of Galactomannan Test with Bronchoalveolar Lavage and Serum for the Diagnosis of Invasive Aspergillosis in Patients with Hematological Malignancies?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Gupta, Ankit; Capoor, Malini R.; Shende, Trupti; Sharma, Bhawna; Mohindra, Ritin; Suri, Jagdish Chander; Gupta, Dipender Kumar
- Publisher
- Medknow Publications; Georg Thieme Verlag KG (ISSN 0974-2727)
- Published
- 2017
- Language
- EN
- Field
- Medicine (Health Sciences)