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Valproic Acid-Induced Kidney Injury Mechanisms by matheus.tenorio is a document available to read on EtoBox.
What is Valproic Acid-Induced Kidney Injury Mechanisms about?
Valproic acid (VPA) is an antiepileptic drug that can cause Fanconi syndrome, characterized by impaired renal tubular transport. Heidari et al. investigated the role of mitochondrial dysfunction and oxidative stress in VPA-induced renal injury using an animal model. Rats treated with VPA showed biochemical evidence of Fanconi syndrome along with increased oxidative stress and mitochondrial impairment in the kidneys. Carnitine supplementation mitigated VPA
- Author
- matheus.tenorio
- Language
- EN