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Novartis Foundation Symposium 289: Growth Factors and Psychiatric Disorders by Lastnovartis Foundation is a nonfiction available to read on EtoBox.

What is Novartis Foundation Symposium 289: Growth Factors and Psychiatric Disorders about?

The recent identification of susceptibility genes for schizophrenia, depression and learning and memory dysfunction suggest that psychiatric disorders may be influenced by a small number of genes with multiple actions. This is the first book to investigate the role of growth factors in these disorders, which should provide clues to the underlying biochemical mechanisms. For example, recent studies have substantiated the provocative finding that __neuregulin 1 (NRG1)__is a candidate gene for schizophrenia. Neuregulin and its receptors, the ErbB tyrosine kinases, are essential for development of the cardiovascular and nervous systems. Lack of NRG1 function may be involved in dysregulation of synaptogenesis and synaptic plasticity in the adult mediated through glutamate receptor function. Polymorphisms for BDNF (brain-derived neurotrophic factor) have also been implicated in the pathogenesis of schizophrenia. BDNF is a prevalent neurotrophic factor that plays an important role in the pathophysiology of depression, bipolar disease and other psychiatric disorders. Other topics addressed in this book include neuroplasticity and neurotrophic factors, signal transduction by neurotrophins,

Who reads Novartis Foundation Symposium 289: Growth Factors and Psychiatric Disorders?

Author

Lastnovartis Foundation

Publisher

John Wiley & Sons, Incorporated

Published

2008

Language

EN

ISBN

9780470516041

Category

nonfiction

Subjects

Medical, Psychology, Medicine