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Can I read NT-proBNP for Risk Prediction in Heart Failure: Identification of Optimal Cutoffs Across Body Mass Index Categories on EtoBox?
NT-proBNP for Risk Prediction in Heart Failure: Identification of Optimal Cutoffs Across Body Mass Index Categories by Giuseppe Vergaro; Francesco Gentile; Laura M.G. Meems; Alberto Aimo; James L. Januzzi; A. Mark Richards; Carolyn S.P. Lam; Roberto Latini; Lidia Staszewsky; Inder S. Anand; Jay N. Cohn; Thor Ueland; Lars Gullestad; Pål Aukrust; Hans-Peter Brunner-La Rocca; Antoni Bayes-Genis; Josep Lupón; Akiomi Yoshihisa; Yasuchika Takeishi; Michael Egstrup; Ida Gustafsson; Hanna K. Gaggin; Kai M. Eggers; Kurt Huber; Greg D. Gamble; Lieng H. Ling; Kui Tong Gerard Leong; Poh Shuah Daniel Yeo; Hean Yee Ong; Fazlur Jaufeerally; Tze P. Ng; Richard Troughton; Robert N. Doughty; Gerry Devlin; Mayanna Lund; Alberto Giannoni; Claudio Passino; Rudolf A. de Boer; Michele Emdin is a Medicine article available to read on EtoBox.
What is NT-proBNP for Risk Prediction in Heart Failure: Identification of Optimal Cutoffs Across Body Mass Index Categories about?
## Objectives: The goal of this study was to assess the predictive power of n-terminal pro-b-type natriuretic peptide (nt-probnp) and the decision cutoffs in heart failure (hf) across body mass index (bmi) categories. ## Background: Concentrations of nt-probnp predict outcome in hf. although the influence of bmi to reduce levels of nt-probnp is known, the impact of obesity on prognostic value remains uncertain. ## Methods: Individual data from the bios (biomarkers in heart failure outpatient study) consortium were analyzed. patients with stable hf were classified as underweight (bmi <18.5 kg/m), normal weight (bmi 18.5-24.9 kg/m), overweight (bmi 25-29.9 kg/m), and mildly (bmi 30-34.9 kg/m), moderately (bmi 35-39.9 kg/m), or severely (bmi ≥40 kg/m) obese. the prognostic role of nt-probnp was tested for the endpoints of all-cause and cardiac death. ## Results: The study population included 12,763 patients (mean age 66 ± 12 years; 25% women; mean left ventricular ejection fraction 33% ± 13%). most patients were overweight (n = 5,176), followed by normal weight (n = 4,299), mildly obese (n = 2,157), moderately obese (n = 612), severely obese (n = 314), and underweight (n = 205). nt-pr
Who reads NT-proBNP for Risk Prediction in Heart Failure: Identification of Optimal Cutoffs Across Body Mass Index Categories?
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- Author
- Giuseppe Vergaro; Francesco Gentile; Laura M.G. Meems; Alberto Aimo; James L. Januzzi; A. Mark Richards; Carolyn S.P. Lam; Roberto Latini; Lidia Staszewsky; Inder S. Anand; Jay N. Cohn; Thor Ueland; Lars Gullestad; Pål Aukrust; Hans-Peter Brunner-La Rocca; Antoni Bayes-Genis; Josep Lupón; Akiomi Yoshihisa; Yasuchika Takeishi; Michael Egstrup; Ida Gustafsson; Hanna K. Gaggin; Kai M. Eggers; Kurt Huber; Greg D. Gamble; Lieng H. Ling; Kui Tong Gerard Leong; Poh Shuah Daniel Yeo; Hean Yee Ong; Fazlur Jaufeerally; Tze P. Ng; Richard Troughton; Robert N. Doughty; Gerry Devlin; Mayanna Lund; Alberto Giannoni; Claudio Passino; Rudolf A. de Boer; Michele Emdin
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)