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This study compares the effectiveness of various photosensitizers in photodynamic therapy (PDT) for treating B16 pigmented melanoma in mice. The results indicate that the tetrabenzamido-substituted zinc(II) naphthalocyanine (ZnNcA) showed the most promising therapeutic effect, significantly delaying tumor growth compared to other sensitizers. The findings suggest that the efficacy of ZnNcA is attributed to its favorable photophysical properties rather than a hyperthermic effect.

Author

Esteban D. Grinbank

Language

EN