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High Dietary Levels of a Conjugated Linoleic Acid Mixture Alter Hepatic Glycerophospholipid Class Profile and Cholesterol-carrying Serum Lipoproteins of Rats by Gabriele I Stangl is a Medicine article available to read on EtoBox.
What is High Dietary Levels of a Conjugated Linoleic Acid Mixture Alter Hepatic Glycerophospholipid Class Profile and Cholesterol-carrying Serum Lipoproteins of Rats about?
To investigate the body composition, hepatic lipids, and serum lipoproteins in response to graded levels of a conjugated linoleic acid (CLA) mixture added to a high linoleate diet, adult male Sprague-Dawley rats were randomly assigned into four dietary groups of 10 rats each and fed for 5 weeks controlled amounts of diets containing 0%, 1%, 3%, or 5% of a CLA mixture in exchange for sunflower oil. The various dietary lipid treatments did not significantly influence growth and body partitioning, although there was a trend toward decreased contents of extractable lipids in carcass (whole bled body without liver and gut) with increasing CLA. When carcass lipids of CLA-treated rats were extracted, a distinct accumulation of total CLA was observed. A dietary level of 1% CLA mixture exhibited only weak effects on hepatic glycerophospholipid levels. CLA levels of 3% and 5% caused distinct changes in phospholipid subclass distribution. These changes were reduced levels of lysophosphatidylethanolamine (LPE) and ethanolamine plasmalogen (EPL) and increased levels of phosphatidylcholine (PC). Further, a 5% level of CLA increased the hepatic concentration of phosphatidylserine (PS) compared wi
Who reads High Dietary Levels of a Conjugated Linoleic Acid Mixture Alter Hepatic Glycerophospholipid Class Profile and Cholesterol-carrying Serum Lipoproteins of Rats?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Gabriele I Stangl
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0955-2863)
- Published
- 2000
- Language
- EN
- Field
- Medicine (Health Sciences)