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Multiple drugs Interstitial Pneumonitis and lack of efficacy: case report A 75-year-old man developed interstitial pneumonitis during treatment with gemcitabine for non-muscle invasive bladder cancer (NMIBC). Additionally, he exhibited lack of efficacy with azithromycin, ceftriaxone, doxycycline, methylprednisolone and piperacillin/tazobactam while being treated for interstitial pneumonitis [not all routes and dosages stated].The man with NMIBC and hypertension along with a history of exercising every day and a remote history of smoking tobacco as a teenager had been on lisinopril and amlodipine for hypertension treatment. He had also been receiving intravesical gemcitabine for recurrent NMIBC in cycles. However, 2 weeks after completing cycle 6, he presented with dry cough and exertional dyspnea of 1-week duration. On examination, he was noted to be hypoxemic to 60% on room air with faintly audible interscapular endinspiratory crackles. Chest x-ray revealed airspace disease within the right lower lung zone. No pulmonary embolism was noted in his CT with angiography of the chest. There were patchy ground-glass opacities in both lungs. Community-acquired pneumonia was assumed.The ma

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Publisher

Springer Science and Business Media LLC

Published

2023

Language

EN

Field

Medicine (Health Sciences)