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The impact of fatigue on mortality of patients with non‐alcoholic fatty liver disease: Data from National Health and nutrition examination survey 2005–2010 and 2017–2018 by Zobair M. Younossi; James M. Paik; Pegah Golabi; Youssef Younossi; Linda Henry; Fatema Nader is a Medicine article available to read on EtoBox.
What is The impact of fatigue on mortality of patients with non‐alcoholic fatty liver disease: Data from National Health and nutrition examination survey 2005–2010 and 2017–2018 about?
## Objective: Fatigue among patients with nafld may negatively impact their health-related quality of life and clinical outcomes (mortality). we determined fatigue prevalence and its association with all-cause mortality among patients with nafld. ## Design: Nhanes 2005-2010 and 2017-2018 data were used with linked mortality data. nafld was defined by fatty liver index for nhanes 2005-2010 and by transient elastography for nhanes 2017-2018. fatigue was assessed by patient health questionnaire. ## Results: Nhanes 2005-2010 cohort (n = 5429, mean age 47.1 years, 49.7% male, 69.9% white), 37.6% had nafld. compared to non-nafld controls, fatigue was more common in nafld (8.35% vs 6.0%, p = .002). among nhanes 2017-2018 cohort (n = 3830, mean age 48.3 years, 48.6% male, 62.3% white), 36.9% had nafld. compared to non-nafld controls, fatigue was more common among nafld (8.7% vs 6.2%). nafld had more sleep disturbance (34.0% vs 26.7%), cardiovascular disease (cvd) (10.7% vs. 6.3%), significant hepatic fibrosis (liver stiffness>8.0 kpa, 17.9% vs 3.5%) and advanced hepatic fibrosis (>13.1 kpa, 5.4% vs 0.9%; all p < .003). the presence of depression (or: 11.52, 95% ci: 4.45-29.80, p < .0001),
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- Author
- Zobair M. Younossi; James M. Paik; Pegah Golabi; Youssef Younossi; Linda Henry; Fatema Nader
- Publisher
- Wiley
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)