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The article presents a transition-metal-free method for synthesizing 4-arylquinolines from anilines and alkynes using K2S2O8 and DMSO, achieving good yields through a one-pot cascade process. This environmentally friendly approach utilizes DMSO as a carbon source and accommodates a variety of substrates with diverse substitution patterns. The study highlights the potential of this method for pharmaceutical applications due to the biological significance of quinoline derivatives.

Author

dougheheh22

Language

EN