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A strategy to prevent a temperature‐induced MRI artifact in warm liquid phantoms due to convection currents by Ryan T. Oglesby; Wilfred W. Lam; Greg J. Stanisz is a Medicine article available to read on EtoBox.

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MRI phantom studies often fail to mimic the temperature of the human body, which can negatively impact accuracy. An artifact induced by increasing temperature in liquid phantoms was observed, presenting a significant challenge to temperature‐controlled experiments. In this study we characterize and provide a solution to eliminate this temperature‐induced MRI artifact. Low concentration (0.5–2.5 mM) agar phantoms were prepared. Utilizing a temperature‐controlled phantom holder, T~1~‐ and T~2~‐weighted structural images were acquired at 7 T along with quantitative B~0~, B~1~, T~1~, T~2~ and ADC maps at both 25 and 37°C. Additionally, computer simulations were conducted to demonstrate the fluid flow and thermal flux patterns in water to provide an insight into the origins of the artifact. Evidence from computer simulation and quantitative MRI strongly suggest the artifact was caused by heat transfer in the form of natural convection leading to structured patterns of signal loss in MR images. The artifact was present up to agar concentrations of 1.5 mM (T~1~ = 3068 ± 16 ms, T~2~ = 1052 ± 20 ms, ADC = 2.29 ± 0.36 × 10^−3^ mm^2^/s at 25°C; T~1~ = 3928 ± 44 ms, T~2~ = 1122 ± 24 ms, ADC =

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Author

Ryan T. Oglesby; Wilfred W. Lam; Greg J. Stanisz

Publisher

Wiley

Published

2021

Language

EN

Field

Medicine (Health Sciences)