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Can I read Gene Therapy for Inherited Retinal Diseases: From Laboratory Bench to Patient Bedside and Beyond on EtoBox?
Gene Therapy for Inherited Retinal Diseases: From Laboratory Bench to Patient Bedside and Beyond by Anand Singh Brar; Deepika C. Parameswarappa; Brijesh Takkar; Raja Narayanan; Subhadra Jalali; Sohini Mandal; Kaoru Fujinami; Srikanta Kumar Padhy is a Medicine article available to read on EtoBox.
What is Gene Therapy for Inherited Retinal Diseases: From Laboratory Bench to Patient Bedside and Beyond about?
This comprehensive review provides a thorough examination of inherited retinal diseases (IRDs), encompassing their classification, genetic underpinnings, and the promising landscape of gene therapy trials. IRDs, a diverse group of genetic conditions causing vision loss through photoreceptor cell death, are explored through various angles, including inheritance patterns, gene involvement, and associated systemic disorders. The focal point is gene therapy, which offers hope for halting or even reversing the progression of IRDs. The review highlights ongoing clinical trials spanning retinal cell replacement, neuroprotection, pharmacological interventions, and optogenetics. While these therapies hold tremendous potential, they face challenges like timing optimization, standardized assessment criteria, inflammation management, vector refinement, and raising awareness among vision scientists. Additionally, translating gene therapy success into widespread adoption and addressing cost-effectiveness are crucial challenges to address. Continued research and clinical trials are essential to fully harness gene therapy’s potential in treating IRDs and enhancing the lives of affected individuals
Who reads Gene Therapy for Inherited Retinal Diseases: From Laboratory Bench to Patient Bedside and Beyond?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Anand Singh Brar; Deepika C. Parameswarappa; Brijesh Takkar; Raja Narayanan; Subhadra Jalali; Sohini Mandal; Kaoru Fujinami; Srikanta Kumar Padhy
- Publisher
- Springer Healthcare
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)