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An magnetic resonance imaging T2\*‐weighted sequence at short echo time to detect putaminal hypointensity in Parkinsonisms by Gennarina Arabia; Maurizio Morelli; Sandra Paglionico; Fabiana Novellino; Maria Salsone; Laura Giofrè; Giusi Torchia; Giuseppe Nicoletti; Demetrio Messina; Francesca Condino; Pierluigi Lanza; Olivier Gallo; Aldo Quattrone is a Medicine article available to read on EtoBox.
What is An magnetic resonance imaging T2\*‐weighted sequence at short echo time to detect putaminal hypointensity in Parkinsonisms about?
## Abstract At 1.5 T, T2\*‐weighted gradient echo (GE) sequences are more sensitive in revealing mineral deposition in the basal ganglia than standard T2 weighted sequences. T2\*‐weighted GE sequences, however, may detect putaminal hypointensities either in patients affected by parkinsonian syndromes or in healthy subjects. The aim of this study was to identify the magnetic resonance imaging (MRI) T2\*‐weighted sequence which more specifically detected putaminal hypointensities differentiating atypical parkinsonian syndromes from Parkinson's disease (PD) and control subjects. In a sample of 38 healthy subjects, we performed three T2\*‐weighted GE sequences at increasing time echo (TE; TE = 15 millisecond, TE = 25 millisecond, and echoplanar at TE = 40 millisecond; T2\* sequences study). The sequence not showing any putaminal abnormality in the healthy subjects was then used to assess putaminal signal intensity in 189 patients with PD, 20 patients with multiple system atrophy (MSA), 41 patients with progressive supranuclear palsy (PSP), and in 150 age and sex‐matched control subjects. In the T2\* sequences study, the T2\*‐weighted TE = 15 (T2\*/15) did not show any putaminal abnorma
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- Author
- Gennarina Arabia; Maurizio Morelli; Sandra Paglionico; Fabiana Novellino; Maria Salsone; Laura Giofrè; Giusi Torchia; Giuseppe Nicoletti; Demetrio Messina; Francesca Condino; Pierluigi Lanza; Olivier Gallo; Aldo Quattrone
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0885-3185)
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)