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Large Kidneys Predict Poor Renal Outcome in Subjects with Diabetes and Chronic Kidney Disease by Vincent Rigalleau; Magalie Garcia; Catherine Lasseur; François Laurent; Michel Montaudon; Christelle Raffaitin; Nicole Barthe; Marie-Christine Beauvieux; Benoit Vendrely; Philippe Chauveau; Christian Combe; Henri Gin is a Medicine article available to read on EtoBox.
What is Large Kidneys Predict Poor Renal Outcome in Subjects with Diabetes and Chronic Kidney Disease about?
## Background: Renal hypertrophy occurs early in diabetic nephropathy, its later value is unknown. do large kidneys still predict poor outcome in patients with diabetes and chronic kidney disease (ckd)? ## Methods: Seventy-five patients with diabetes and ckd according to a glomerular filtration rate (gfr, by 51cr-edta clearance) below 60 ml/min/1.73 m2 or an albumin excretion rate above 30 mg/24 h, had an ultrasound imaging of the kidneys and were cooperatively followed during five years by the diabetology and nephrology departments of the centre hospitalier universitaire de bordeaux. ## Results: The patients were mainly men (44/75), aged 62 +/- 13 yrs, with long-standing diabetes (duration:17 +/- 9 yrs, 55/75 type 2), and ckd: initial gfr: 56.5 (8.5-209) ml/min/1.73 m2, aer: 196 (20-2358) mg/24 h. their mean kidney lenght (108 +/- 13 mm, 67-147) was correlated to the gfr (r = 0.23, p < 0.05). during the follow-up, 9/11 of the patients who had to start dialysis came from the half with the largest kidneys (logrank: p < 0.05), despite a 40% higher initial isotopic gfr. serum creatinine were initially lower (small kidneys: 125 (79-320) micromol/l, large: 103 (50-371), p < 0.05), but s
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- Author
- Vincent Rigalleau; Magalie Garcia; Catherine Lasseur; François Laurent; Michel Montaudon; Christelle Raffaitin; Nicole Barthe; Marie-Christine Beauvieux; Benoit Vendrely; Philippe Chauveau; Christian Combe; Henri Gin
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2000-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1471-2369)
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)