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Predictive Factors for Gastrostomy at Time of Diagnosis and Impact on Survival in Patients with Amyotrophic Lateral Sclerosis by Vergonjeanne, Marion; Fayemendy, Philippe; Marin, Benoit; Penoty, Marie; Lautrette, Géraldine; Sourisseau, Huguette; Preux, Pierre-Marie; Desport, Jean-Claude; Couratier, Philippe; Jésus, Pierre is a Medicine article available to read on EtoBox.
What is Predictive Factors for Gastrostomy at Time of Diagnosis and Impact on Survival in Patients with Amyotrophic Lateral Sclerosis about?
## Background: Gastrostomy is recommended in patients with amyotrophic lateral sclerosis (als) in the presence of weight loss over 10% as compared to usual weight, repeated aspirations or meal time duration longer than 45 min. currently, the impact of gastrostomy on survival of als patients is not clear. ## Aims: I) to describe diagnosis factors associated with the indication for gastrostomy ii) to evaluate survival of als patients with gastrostomy indication according to their acceptance of feeding tube placement. ## Methods: Patients with als were included and followed in the als referral centre of limoges's teaching hospital between 2006 and 2017. neurological, nutritional and respiratory status was assessed prospectively from diagnosis to death. statistical analysis was performed using mann-whitney test, chi tests, cox model and multivariate logistic regression. ## Results: Two hundred and eighty-five patients were included. among the 182 for whom gastrostomy was indicated, 63.7% accepted the placement. the median time was 7.3 months [iqr: 3.2-15.0] and 2.7 months [iqr: 0.9-5.8] respectively from diagnosis to indication and from indication to placement. weight loss >5% signific
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- Author
- Vergonjeanne, Marion; Fayemendy, Philippe; Marin, Benoit; Penoty, Marie; Lautrette, Géraldine; Sourisseau, Huguette; Preux, Pierre-Marie; Desport, Jean-Claude; Couratier, Philippe; Jésus, Pierre
- Publisher
- Elsevier Science; Elsevier ; Churchill Livingstone; Elsevier BV (ISSN 0261-5614)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)