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Membrane Contact Sites and Organelles Interaction in Plant Autophagy by Ye, Hao; Ji, Changyang; Guo, Rongfang; Jiang, Liwen is a Agricultural and Biological Sciences article available to read on EtoBox.

What is Membrane Contact Sites and Organelles Interaction in Plant Autophagy about?

Autophagy is an intracellular trafficking and degradation system for recycling of damaged organelles, mis-folded proteins and cytoplasmic constituents. Autophagy can be divided into non-selective autophagy and selective autophagy according to the cargo specification. Key to the process is the timely formation of the autophagosome, a double-membrane structure which is responsible for the delivery of damaged organelles and proteins to lysosomes or vacuoles for their turnover. Autophagosomes are formed by the closure of cup-shaped phagophore which depends on the proper communication with membrane contributors. The endoplasmic reticulum (ER) is a major membrane source for autophagosome biogenesis whereby the ER connects with phagophore through membrane contact sites (MCSs). MCSs are closely apposed domains between organelle membranes where lipids and signals are exchanged. Lipid transfer proteins (LTPs) are a large family of proteins including Oxysterol-binding protein related proteins (ORP) which can be found at MCSs and mediate lipid transfer in mammals and yeast. In addition, interaction between autophagosomes and other organelles can also be detected in selective autophagy for sele

Who reads Membrane Contact Sites and Organelles Interaction in Plant Autophagy?

Author

Ye, Hao; Ji, Changyang; Guo, Rongfang; Jiang, Liwen

Publisher

Frontiers Media SA; Frontiers Media S.A.; Lausanne: Frontiers Media S.A., 2010- (ISSN 1664-462X)

Published

2020

Language

EN

Field

Agricultural and Biological Sciences (Life Sciences)