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Modified xanthan gum for buccal delivery—A promising approach in treating sialorrhea by Flavia Laffleur,Martina Michalek is a scholarly article available to read on EtoBox.

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International Journal of Biological Macromolecules, 102 (2017) 1250-1256. doi:10.1016/j.ijbiomac.2017.04.123 Modified xanthan gum for buccal delivery—A promising approach in treating sialorrhea 1 1 Introduction 1 2 Materials and methods 2 2.1 Materials 2 2.2 Synthesis of modified xanthan 2 2.3 Characterization of modified xanthan 2 2.4 Swelling and erosion studies 2 2.5 Study of salivary reduction 2 2.6 Water vapor assay 2 2.7 Contact angle 3 2.8 In vitro evaluation of drug release 3 2.9 CellTiter-Glo® luminescent cell viability assay 3 2.10 Statistical data analysis 3 3 Results and discussion 3 3.1 Synthesis and characterization of modified xanthan 3 3.2 Cytotoxicity investigations 4 3.3 Swelling properties 4 3.4 Study of salivary reduction 4 3.5 Water vapor uptake 5 3.6 Mucoadhesive assay-contact angle 5 3.7 Drug release of tannin 5 3.8 Safety investigation 5 4 Conclusion 5 Declaration of interest 7 Acknowledgement 7 References 7 Buccal,Sialorrhea,Mucoadhesion,Tannin,Xanthan

Author

Flavia Laffleur,Martina Michalek

Publisher

Elsevier B.V.