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Can I read Brown propolis-metabolomic innovative approach to determine compounds capable of killing Staphylococcus aureus biofilm and Trichomonas vaginalis on EtoBox?
Brown propolis-metabolomic innovative approach to determine compounds capable of killing Staphylococcus aureus biofilm and Trichomonas vaginalis by Djaceli Sampaio de Oliveira Dembogurski; Danielle Silva Trentin; Amanda Galdi Boaretto; Graziela Vargas Rigo; Rodrigo Campos da Silva; Tiana Tasca; Alexandre José Macedo; Carlos Alexandre Carollo; Denise Brentan Silva is a Agricultural and Biological Sciences article available to read on EtoBox.
What is Brown propolis-metabolomic innovative approach to determine compounds capable of killing Staphylococcus aureus biofilm and Trichomonas vaginalis about?
Propolis, a resin produced by bees, is widely used in industrial products, including food, cosmetics, supplements, and pharmaceuticals. Extracts (ethanolic and hydroethanolic) and fractions, yielded by accelerated solvent extraction methodology, were obtained from different samples of Brazilian brown propolis (BBP). They were evaluated for antioxidant capacity, antibacterial, antibiofilm, and anti-Trichomonas vaginalis activities. The metabolomics profiling was determined by LC-DAD-MS and an innovative application of statistical analyses (univariate and chemometrics) was applied to correlate chemical compounds with biological activities. Eighty-six compounds were identified, including phenylpropanoic acids, flavonoids, chlorogenic acids, and prenylated phenylpropanoic acids. Propolis-fractions killed about 93% of Staphylococcus aureus in biofilm (at concentration of 125 μg/mL), showed activity against T. vaginalis with MIC at 400 μg/mL and significative antioxidant capacity (IC 2.32-3.80 μg/mL). Propolis extracts and fractions did not show antibacterial and antibiofilm activities against Pseudomonas aeruginosa. The prenylated phenylpropanoic acids positively correlated with both th
Who reads Brown propolis-metabolomic innovative approach to determine compounds capable of killing Staphylococcus aureus biofilm and Trichomonas vaginalis?
It is typically read by researchers, students, and practitioners in Agricultural and Biological Sciences.
- Author
- Djaceli Sampaio de Oliveira Dembogurski; Danielle Silva Trentin; Amanda Galdi Boaretto; Graziela Vargas Rigo; Rodrigo Campos da Silva; Tiana Tasca; Alexandre José Macedo; Carlos Alexandre Carollo; Denise Brentan Silva
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0963-9969)
- Published
- 2018
- Language
- EN
- Field
- Agricultural and Biological Sciences (Life Sciences)