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The Role of Mitochondria in Redox Signaling of Muscle Homeostasis by Li Li Ji; Dongwook Yeo; Chounghun Kang; Tianou Zhang is a Medicine article available to read on EtoBox.

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## Highlights •Mitochondrion plays a critical role in controlling exercise-induced adaptive responses through coordination of redox signaling. •Mitostasis is regulated by mitochondrial biogenesis, fusion and fission dynamics, and mitophagy, and their functional integrity is crucial for muscle contraction. •Muscle immobilization could promote ubiquitin proteolysis, mitophagy, and inflammation via activating nuclear factor-κB and forkhead box O signaling. •Stimulation of PGC-1α signaling through exercise or experimental approach enhances muscle protein preservation, mitochondrial stability, and resistance to oxidative stress and inflammation. •Future research will continue to explore the mechanism and application of improved mitochondrial homeostasis in health issues that induce muscle atrophy.

Who reads The Role of Mitochondria in Redox Signaling of Muscle Homeostasis?

Author

Li Li Ji; Dongwook Yeo; Chounghun Kang; Tianou Zhang

Publisher

Elsevier BV

Published

2020

Language

EN

Field

Medicine (Health Sciences)