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## PURPOSE: The goal of this investigation is to establish strategies for the imaging of nuclei other than protons. Due to the vastly reduced physiological abundance compared to lH, signal strength is currently a fundamental concern for non-proton imaging. Attention is focused here on predicting and optimizing SIN (signal-to-noise). The twelve physiologically most abundant elements are examined, and a listing of relevent nuclear parameters and predicted S/N for 1H and the next four "most likely" isotopes is presented. The significance of particular nuclear parameters with respect to experimental methods and instrumental limitations or requirements is discussed. A comparison is made to empirical observations. METHODS: S/N models were similar to those used by previous workers Ell. Nuclear constants of isotopes and physiological data were taken from standard references C2,33 and relaxation times were obtained from reference works C43 and the literature. 23Na and 1H NMR signals and images from human samples were obtained with Picker developmental .5 and 1.5 Tesla whole-body NMR imaging systems. RESULTS: A compilation of nuclear parameters and S/N estimates is shown in Table 1. The resu

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Publisher

Wiley (John Wiley & Sons); Wiley (ISSN 1065-9889)

Published

1984

Language

EN

Field

Medicine (Health Sciences)