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Automated Design of Pin-constrained Digital Microfluidic Arrays for Lab-on-a-chip Applications\* by William L. Hwang; Fei Su; Krishnendu Chakrabarty is a scholarly article available to read on EtoBox.

What is Automated Design of Pin-constrained Digital Microfluidic Arrays for Lab-on-a-chip Applications\* about?

Microfluidics-based biochips, also referred to as lab-on-a-chip (LoC), are devices that integrate fluid-handling functions such as sample preparation, analysis, separation, and detection. This emerging technology combines electronics with biology to open new application areas such as point-of-care diagnosis, on-chip DNA analysis, and automated drug discovery. We propose a design automation method for pin-constrained LoCs that manipulate nanoliter volumes of discrete droplets on a microfluidic array. In contrast to the direct-addressing scheme that has been studied thus far in the literature, we assign a small number of independent control pins to a large number of electrodes in the LoC, thereby reducing design complexity and product cost. We apply the proposed method to a microfluidic array for a set of multiplexed bioassays.

Author

William L. Hwang; Fei Su; Krishnendu Chakrabarty

Publisher

ACM Press

Published

2006

Language

EN