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Quality of Life After Non-surgical Treatment of Anal Carcinoma: a Case Control Study of Long-term Survivors by C.R. Jephcott; C. Paltiel; J. Hay is a Agricultural and Biological Sciences article available to read on EtoBox.

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Aims: To evaluate the quality of life (QOL) of a cohort of patients after non-surgical treatment of anal carcinoma with chemotherapy and radiation. Materials and methods: Patients treated for anal carcinoma at the British Columbia Cancer Agency between 1990 and 2001 were identified from audit data. A total of 92 suitable patients were found among these. They were approached by letter and encouraged to complete questionnaires regarding their QOL. The European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 and EORTC QLQ-CR38 instruments were used to evaluate general QOL, and more disease and site-related aspects. Fifty responses were received and were compared with those of a sample of matched local volunteer control participants who had not received any treatment to their abdomen or pelvis. Responses were scored and the results analysed with the SPSS statistical package. Results: Significant differences were detected in global QOL and in more specific areas of both general and site/disease-specific nature. Identified general areas involved physical, social, and role functions, and symptoms of fatigue, nausea and vomiting, dyspnoea, appetite loss, diarrhoea, consti

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Author

C.R. Jephcott; C. Paltiel; J. Hay

Publisher

Elsevier Science; Springer; Elsevier ; Springer-Verlag; W. B. Saunders Co., Ltd.; Springer Verlag; Elsevier BV; Springer Science and Business Media LLC (ISSN 1433-2981)

Published

2004

Language

EN

Field

Agricultural and Biological Sciences (Life Sciences)