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What is Hypothermia Treatment for Neonatal Encephalopathy about?

1. Neonatal encephalopathy can occur in 1-6 per 1,000 live term births and is caused by hypoxic-ischemic insult during birth. It can lead to death or disabilities. 2. The pathophysiology involves primary and secondary energy failure. Primary failure is caused by reduced blood flow and oxygen, leading to decreased ATP and cell acidosis. Secondary failure involves inflammation, apoptosis, and excitotoxicity. 3. Current treatment focuses on supportive care, but hypothermia initiated within 6 hours and maint

Author

Javier Miranda Mallea

Language

EN