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Computational Fluid Dynamics in Coronary Artery Disease by Zhonghua Sun; Lei Xu is a Medicine article available to read on EtoBox.

What is Computational Fluid Dynamics in Coronary Artery Disease about?

Computational fluid dynamics (CFD) is a widely used method in mechanical engineering to solve complex problems by analysing fluid flow, heat transfer, and associated phenomena by using computer simulations. In recent years, CFD has been increasingly used in biomedical research of coronary artery disease because of its high performance hardware and software. CFD techniques have been applied to study cardiovascular haemodynamics through simulation tools to predict the behaviour of circulatory blood flow in the human body. CFD simulation based on 3D luminal reconstructions can be used to analyse the local flow fields and flow profiling due to changes of coronary artery geometry, thus, identifying risk factors for development and progression of coronary artery disease. This review aims to provide an overview of the CFD applications in coronary artery disease, including biomechanics of atherosclerotic plaques, plaque progression and rupture; regional haemodynamics relative to plaque location and composition. A critical appraisal is given to a more recently developed application, fractional flow reserve based on CFD computation with regard to its diagnostic accuracy in the detection of h

Who reads Computational Fluid Dynamics in Coronary Artery Disease?

Author

Zhonghua Sun; Lei Xu

Publisher

Elsevier BV

Published

2014

Language

EN

Field

Medicine (Health Sciences)