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This study characterizes the genetic and genomic features of 462 melanoma patient-derived xenografts (PDX), tumor biopsies, and cell lines, identifying major and minor melanoma subtypes and their associated mutations. The research highlights the genetic diversity of melanoma, with samples from both treatment-naïve and previously treated patients, and establishes a resource for future drug development and biological studies. The findings underscore the importance of genetically-annotated models in advancing
- Author
- fatfatwolf999
- Language
- EN