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What is Feline Coronaviruses and FIP Pathogenesis about?

This document summarizes our current knowledge about feline coronaviruses (FCoVs) that cause feline infectious peritonitis (FIP). It discusses the taxonomy, genome organization, and accessory genes/proteins of FCoVs. It describes how FCoVs exist as two biotypes - feline enteric coronavirus (FECV) which causes mild enteritis and feline infectious peritonitis virus (FIPV) which causes fatal FIP. Mutations in the spike protein are thought to allow FECV to switch to the lethal FIPV form. The precise roles of th

Author

Juan Duaso

Language

EN