Can I read Adalimumab treatment for chronic recurrent Vogt-Koyanagi-Harada disease with sunset glow fundus: A multicenter study on EtoBox?

Adalimumab treatment for chronic recurrent Vogt-Koyanagi-Harada disease with sunset glow fundus: A multicenter study by Masaru Takeuchi; Shunsaku Nakai; Yoshihiko Usui; Kenichi Namba; Kayo Suzuki; Yosuke Harada; Sentaro Kusuhara; Toshikatsu Kaburaki; Rie Tanaka; Masaki Takeuchi; Nobuhisa Mizuki; Kei Nakai; Hiroshi Goto; Carl P. Herbort is a Medicine article available to read on EtoBox.

What is Adalimumab treatment for chronic recurrent Vogt-Koyanagi-Harada disease with sunset glow fundus: A multicenter study about?

## PURPOSE: We investigated the efficacy and safety of adalimumab (ADA) treatment for chronic recurrent Vogt-Koyanagi-Harada (VKH) patients with sunset glow fundus (SGF). ## METHODS: Medical records of 50 chronic recurrent VKH patients with SGF who received ADA treatment for more than 6 months were retrospectively reviewed. ## RESULTS: The mean age of chronic recurrent VKH patients with SGF was 55.9 ± 14.4 years, and the male/female ratio was 26/24. Before ADA treatment, the mean daily dose of systemic corticosteroids was 16.5 ± 12.7 mg, and 22 patients (44%) were under immunosuppressors. LogMAR visual acuity (VA), flare counts, subfoveal choroidal thickness (SFCT), indocyanine green angiography scores, and corticosteroid and cyclosporine doses were significantly reduced by ADA treatment at 6 months compared to baseline. Among all parameters, flare count was significantly related to LogMAR VA. LogMAR VA was significantly related to flare counts but not to SFCT nor to ICGA scores. ADA treatment was continued in 94%. ## CONCLUSION: ADA was shown to be effective in achieving remission of chronic recurrent VKH disease with SGF refractory to conventional treatments, and was generally we

Who reads Adalimumab treatment for chronic recurrent Vogt-Koyanagi-Harada disease with sunset glow fundus: A multicenter study?

Author

Masaru Takeuchi; Shunsaku Nakai; Yoshihiko Usui; Kenichi Namba; Kayo Suzuki; Yosuke Harada; Sentaro Kusuhara; Toshikatsu Kaburaki; Rie Tanaka; Masaki Takeuchi; Nobuhisa Mizuki; Kei Nakai; Hiroshi Goto; Carl P. Herbort

Publisher

Medknow

Published

2022

Field

Medicine (Health Sciences)