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Can I read The preliminary analysis of lymphatic flow around the connective tissues surrounding SMA and SpA elucidates patients’ oncological condition in borderline-resectable pancreatic cancer on EtoBox?

The preliminary analysis of lymphatic flow around the connective tissues surrounding SMA and SpA elucidates patients’ oncological condition in borderline-resectable pancreatic cancer by Hirofumi Akita; Kei Asukai; Yosuke Mukai; Shinichiro Hasegawa; Takeshi Omori; Hiroshi Miyata; Masayuki Ohue; Masato Sakon; Hiroshi Wada; Hidenori Takahashi is a Medicine article available to read on EtoBox.

What is The preliminary analysis of lymphatic flow around the connective tissues surrounding SMA and SpA elucidates patients’ oncological condition in borderline-resectable pancreatic cancer about?

## Background In pancreatic ductal adenocarcinoma (PDAC), invasion of connective tissues surrounding major arteries is a crucial prognostic factor after radical resection. However, why the connective tissues invasion is associated with poor prognosis is not well understood. ## Materials and methods From 2018 to 2020, 25 patients receiving radical surgery for PDAC in our institute were enrolled. HyperEye Medical System (HEMS) was used to examine lymphatic flow from the connective tissues surrounding SMA and SpA and which lymph nodes ICG accumulated in was examined. ## Results HEMS imaging revealed ICG was transported down to the paraaortic area of the abdominal aorta along SMA. In pancreatic head cancer, 9 paraaortic lymph nodes among 14 (64.3%) were ICG positive, higher positivity than LN#15 (25.0%) or LN#18 (50.0%), indicating lymphatic flow around the SMA was leading directly to the paraaortic lymph nodes. Similarly, in pancreatic body and tail cancer, the percentage of ICG-positive LN #16a2 was very high, as was that of #8a, although that of #7 was only 42.9%. ## Conclusions Our preliminary result indicated that the lymphatic flow along the connective tissues surrounding major a

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Author
Hirofumi Akita; Kei Asukai; Yosuke Mukai; Shinichiro Hasegawa; Takeshi Omori; Hiroshi Miyata; Masayuki Ohue; Masato Sakon; Hiroshi Wada; Hidenori Takahashi
Publisher
Springer Science and Business Media LLC
Published
2024
Language
EN
Field
Medicine (Health Sciences)