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Micronization of the officinal component emodin via the SEDS process through prefilming atomization by Hai Long Hong; Quan Ling Suo; Zhong Min Lang; Li Min Han; Chun Ping Li is a Materials Science article available to read on EtoBox.

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## Abstract The micronization of emodin in a mixed solution of dichloromethane and methanol by the Solution Enhanced Dispersion by Supercritical Fluids through Prefilming Atomization (SEDS‐PA) process has been successfully performed. Morphologies and particle sizes (PSs) of the emodin microparticles were analyzed by scanning electron microscopy. The results of micronization show that the acicular or rod‐like emodin crystals with PSs of about 3‐10 μm wide and 100‐300 μm long have successfully been micronized to needle‐like, rod‐like, twisted fiber‐like and coalesced net‐like microparticles with PSs of about 0.1‐1.0μm wide and 2‐40μm long by the SEDS‐PA process. The effect of technological conditions on micronization has been studied. With the increase of initial solution concentration and temperature, the PSs of emodin microparticles increase. With the increase of solution flow rate and pressure, the PSs of emodin microparticles decrease. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)

Who reads Micronization of the officinal component emodin via the SEDS process through prefilming atomization?

Author

Hai Long Hong; Quan Ling Suo; Zhong Min Lang; Li Min Han; Chun Ping Li

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); Wiley - V C H Verlag GmbbH & Co.; Wiley (ISSN 0232-1300)

Published

2008

Language

EN

Field

Materials Science (Physical Sciences)