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Glutamate serves as an excitatory neurotransmitter in the central nervous system, synthesized primarily from α-ketoglutarate and involved in various biochemical reactions. The glutamine cycle facilitates the recycling of glutamate between neurons and astrocytes, maintaining metabolic balance and preventing loss of α-ketoglutarate from the TCA cycle. Glutamate receptors, categorized into ionotropic and metabotropic types, play crucial roles in synaptic transmission and are regulated by various ligands and io

Author

fatimamuz

Language

EN