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What is Mechanical about?
This study presents a mechanistic modeling framework for the primary drying of frozen particulate beds, specifically focusing on thin-film freeze-drying (TFFD) processes. The model integrates experimentally measured parameters and predicts drying kinetics, demonstrating that particle geometry and packing significantly influence drying rates and temperature profiles. The framework aims to optimize drying protocols and enhance the design of lyophilized products by providing insights into heat and mass transfe
- Author
- Ganesamoorthy Thirunarayanan
- Language
- EN