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Left Bundle Branch Pacing Versus Biventricular Pacing for Acute Cardiac Resynchronization in Patients With Heart Failure by Yixiu Liang; Jingfeng Wang; Xue Gong; Hongyang Lu; Ziqing Yu; Lei Zhang; Minghui Li; Lei Pan; Xueying Chen; Jie Cui; Weiwei Zhang; Ruogu Li; Xiaohong Zhou; Weijian Huang; Yangang Su; Junbo Ge is a Medicine article available to read on EtoBox.
What is Left Bundle Branch Pacing Versus Biventricular Pacing for Acute Cardiac Resynchronization in Patients With Heart Failure about?
## Background: Left bundle branch pacing (LBBP) has emerged as an alternative to biventricular pacing (BVP) for delivering cardiac resynchronization therapy. We sought to compare the acute improvement of electrical and mechanical synchrony, and hemodynamics between LBBP and BVP in patients with heart failure and left bundle branch block. ## Methods: LBBP and BVP were performed and compared in a crossover fashion in patients with heart failure and left bundle branch block undergoing cardiac resynchronization therapy implantation. Electrical synchrony was assessed by QRS duration and area, mechanical synchrony by the SD of time to peak velocity of 12 left ventricular segments (Ts-SD) and interventricular mechanical delay, and hemodynamics by the maximum rate of left ventricular pressure rise (dP/dt~max~). ## Results: Twenty-one patient with heart failure and left bundle branch block (mean age 67±10 years, 48% male, and 90% nonischemic cause) were included. Both LBBP and BVP provided significant improvements in electrical and mechanical synchrony, and hemodynamics compared to the baseline. Compared with BVP, LBBP achieved a larger reduction in QRS duration (−11 ms [95% CI, −17 to −4 m
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- Author
- Yixiu Liang; Jingfeng Wang; Xue Gong; Hongyang Lu; Ziqing Yu; Lei Zhang; Minghui Li; Lei Pan; Xueying Chen; Jie Cui; Weiwei Zhang; Ruogu Li; Xiaohong Zhou; Weijian Huang; Yangang Su; Junbo Ge
- Publisher
- Ovid Technologies (Wolters Kluwer Health)
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)