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Variation in the Prevalence of Congenital Heart Defects by Maternal Race/Ethnicity and Infant Sex by Wendy N. Nembhard; Tao Wang; Melissa L. Loscalzo; Jason L. Salemi is a Medicine article available to read on EtoBox.

What is Variation in the Prevalence of Congenital Heart Defects by Maternal Race/Ethnicity and Infant Sex about?

## Objective: To determine the prevalence of major congenital heart defects (chd) by ethnicity and sex. ## Study design: Data from the florida birth defects registry was used to conduct a retrospective cohort study with 8029 singleton infants with 11 chds born 1998-2003 to resident non-hispanic (nh) white, nh-black, and hispanic women aged 15 to 49. defect-specific prevalence rates, ratios, and 95% confidence intervals were calculated. poisson regression was used to calculate adjusted ethnic-specific rate ratios (rr) for each chd. statistical significance was p < .0001. ## Results: Compared with nh-whites, nh-black males had significantly increased rates of pulmonary valve atresia/stenosis (rr = 1.66) but lower prevalence of aortic valve atresia/stenosis (rr = 0.33) and ventricular septal defect (vsd; rr = 0.78). hispanic males had lower rates of aortic valve atresia/stenosis (rr = 0.28), coarctation of the aorta (rr = 0.61) and vsd (rr = 0.79). nh-black females had statistically significantly lower rates of vsd (rr = 0.75), and hispanic females had lower rates of tetralogy of fallot (rr = 0.54), vsd (rr = 0.84) and atrioventricular septal defects (rr = 0.53) compared with nh-white

Who reads Variation in the Prevalence of Congenital Heart Defects by Maternal Race/Ethnicity and Infant Sex?

Author

Wendy N. Nembhard; Tao Wang; Melissa L. Loscalzo; Jason L. Salemi

Publisher

Elsevier BV

Published

2010

Language

EN

Field

Medicine (Health Sciences)