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The study investigates the role of the HDAC9 gene in the replication of the Foot-and-Mouth Disease Virus (FMDV) using CRISPR/Cas9 technology to create HDAC9 knockout (KO) BHK-21 cells. Results indicate that HDAC9-KO cells exhibit significantly enhanced FMDV replication compared to control cells, with increased viral RNA and protein expression. The findings suggest that HDAC9 may play a critical role in the host

Author

Jitender Rathee

Language

EN