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The document details a novel synthesis method for penicillin N and isopenicillin N using allyl-type protective groups, which enhances yield and stability compared to previous methods. The process involves selective hydrolysis and acylation of 2-(N-allyloxycarbonyl)aminoadipic acid derivatives, followed by catalytic allyl transfer for deprotection. This approach offers a straightforward and efficient route to these important compounds, which are crucial for biosynthesis studies in penicillins and cephalospor

Author

franvaldez0900

Language

EN