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What is Chronic Lymphocytic Leukemia Case Study about?
This case report describes a patient with a history of chronic lymphocytic leukemia (CLL) who developed plasmablastic lymphoma after receiving multiple lines of chemotherapy treatment for CLL over several years. Biopsy of an inguinal lymph node revealed a plasmablastic neoplasm that was CD138, CD38, and IRF4 positive by immunohistochemistry. Cytogenetic testing found deletions of TP53 and gains of ATM, as well as a MYC translocation. This represents an uncommon type of Richter transformation from CLL to an
- Author
- Christopher Julien
- Language
- EN