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The article presents a novel Pd/C–H2 catalytic system for the one-pot oxidative aromatization and deoxygenation of dihydropyridinedione derivatives, yielding alkyl-substituted pyridines with high efficiency and selectivity. This method operates under mild conditions using ethanol as a green solvent and atmospheric hydrogen pressure, generating water as the only by-product. The approach offers a sustainable and scalable alternative to traditional, harsher methods for synthesizing alkyl pyridines, showcasing

Author

Thư Trần

Language

EN