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Bioresorption Control and Biological Response of Magnesium Alloy AZ31 Coated with Poly-β-Hydroxybutyrate by Wang, Lu (author);Aversa, Raffaella (author);Houa, Zhengjun (author);Tian, Jie (author);Liang, Shuang (author);Ge, Shuping (author);Chen, Yu (author);Perrotta, Valeria (author);Apicella, Antonio (author);Apicella, Davide (author);Cioffi, Luigi (author);Wang, Guixue (author) is a Engineering article available to read on EtoBox.

What is Bioresorption Control and Biological Response of Magnesium Alloy AZ31 Coated with Poly-β-Hydroxybutyrate about?

Magnesium and its alloys are not normally used as bioresorbable temporary implants due to their high and uncontrolled degradation rate in a physiological liquid environment. The improvement of corrosion resistance to simulated body fluids (SBF) of a magnesium alloy (AZ31) coated with poly-β-hydroxybutyrate (PHB) was investigated. Scanning electron microscopy, Fourier transform infrared spectrometer, and contact angle measurements were used to characterize surface morphology, material composition, and wettability, respectively. pH modification of the SBF corroding medium, mass of Mg2+ ions released, weight loss of the samples exposed to the SBF solution, and electrochemical experiments were used to describe the corrosion process and its kinetics. The material’s biocompatibility was described by evaluating the effect of corrosion by products collected in the SBF equilibrating solution on hemolysis ratio, cytotoxicity, nitric oxide (NO), and total antioxidant capacity (T-AOC). The results showed that the PHB coating can diffusively control the degradation rate of magnesium alloy, improving its biocompatibility: the hemolysis rate of materials was lower than 5%, while in vitro human um

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It is typically read by researchers, students, and practitioners in Engineering.

Author
Wang, Lu (author);Aversa, Raffaella (author);Houa, Zhengjun (author);Tian, Jie (author);Liang, Shuang (author);Ge, Shuping (author);Chen, Yu (author);Perrotta, Valeria (author);Apicella, Antonio (author);Apicella, Davide (author);Cioffi, Luigi (author);Wang, Guixue (author)
Publisher
MDPI AG
Published
2021
Language
EN
Field
Engineering (Physical Sciences)

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