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Non-Helicobacter pylori Gastric Microbiome Modulates Prooncogenic Responses and Is Associated With Gastric Cancer Risk by Ryota Niikura,Yoku Hayakawa,Naoyoshi Nagata,Tohru Miyoshi-Akiayama,Koji Miyabayashi,Mayo Tsuboi,Nobumi Suzuki,Masahiro Hata,Junya Arai,Ken Kurokawa,Sohei Abe,Chie Uekura,Kotaro Miyoshi,Sozaburo Ihara,Yoshihiro Hirata,Atsuo Yamada,Hiroaki Fujiwara,Tetsuo Ushiku,Susan L. Woods,Daniel L. Worthley,Masanori Hatakeyama,Yiping W. Han,Timothy C. Wang,Takashi Kawai,Mitsuhiro Fujishiro is a nonfiction available to read on EtoBox.

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Gastro Hep Advances, 2 (2023) 684-700. doi:10.1016/j.gastha.2023.03.010 Non-Helicobacter pylori Gastric Microbiome Modulates Prooncogenic Responses and Is Associated With Gastric Cancer Risk 1 Introduction 2 Results 2 Gastric dysbiosis is associated with incidence of gastric cancer following H. pylori eradication 2 Fusobacterium and Neisseria spp. stimulate gastric epithelial cells and activate proinflammatory and prooncogenic pathways 4 Fusobacterium and Neisseria spp. accelerate proinflammatory responses in mice 7 Gastric mucin plays a role in defense against mucosal pathogens 7 Fusobacterium, but not Neisseria, species induce double-strand breaks via metabolite secretion 9 Fusobacterium and Neisseria spp. are frequently detected in gastric cancer tissues and associated with immune signatures an ... 11 Discussion 11 Materials and Methods 15 Patient characteristics 15 Cohort data source 15 Inclusion and exclusion criteria 15 Upper gastrointestinal endoscopy, sample collection, histological examination, and patient follow-up 15 Outcome and clinical variables 15 Conclusion 15 Supplementary Material 16 References 16 Acknowledgments: 17 Authors' Contributions: 17 16SrRNA,Gastric Micro

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Author

Ryota Niikura,Yoku Hayakawa,Naoyoshi Nagata,Tohru Miyoshi-Akiayama,Koji Miyabayashi,Mayo Tsuboi,Nobumi Suzuki,Masahiro Hata,Junya Arai,Ken Kurokawa,Sohei Abe,Chie Uekura,Kotaro Miyoshi,Sozaburo Ihara,Yoshihiro Hirata,Atsuo Yamada,Hiroaki Fujiwara,Tetsuo Ushiku,Susan L. Woods,Daniel L. Worthley,Masanori Hatakeyama,Yiping W. Han,Timothy C. Wang,Takashi Kawai,Mitsuhiro Fujishiro

Publisher

The Authors

Language

EN

Category

nonfiction