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What is Understanding Autoimmunity Mechanisms about?
Autoimmunity is caused by a problem with self/non-self discrimination. Several mechanisms can trigger autoimmune diseases, including the release of sequestered antigens, molecular mimicry between foreign and self-antigens, alterations in antigen processing, infections, and genetic factors. Lymphocyte abnormalities, a failure of central tolerance, and polyclonal lymphocyte activation can also lead to autoimmunity by overcoming peripheral tolerance. Rheumatoid arthritis is an autoimmune disorder that results
- Author
- Malliga Sundareshan
- Language
- EN