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Can I read Near-infrared Magnetic Core-shell Nanoparticles Based on Lanthanide Metal-organic Frameworks as a Ratiometric Felodipine Sensing Platform on EtoBox?
Near-infrared Magnetic Core-shell Nanoparticles Based on Lanthanide Metal-organic Frameworks as a Ratiometric Felodipine Sensing Platform by Yu-Peng Jiang; Xin-Hui Fang; Qian Wang; Jian-Zhong Huo; Yuan-Yuan Liu; Xin-Rui Wang; Bin Ding is a Chemistry article available to read on EtoBox.
What is Near-infrared Magnetic Core-shell Nanoparticles Based on Lanthanide Metal-organic Frameworks as a Ratiometric Felodipine Sensing Platform about?
Felodipine is an effective drug to treat hypertension, but its abuse can cause bardycardia. It is significant to develop highly sensitive detection platform for felodipine to enable the efficient treatment of hypertension diseases. In this work, to highly efficiently detect felodipine, multi-emission near-infrared (NIR) hierarchical magnetic core-shell lanthanide-MOF nanoparticles, namely Nd-MOF@Yb-MOF@SiO~2~@Fe~3~O~4~ (**NIR-1**), has been synthesized by layer-by-layer (LBL) method. LBL method can adjust the optical properties of **NIR-1** and expose more active sites to improve sensitivity in detection process. **NIR-1** has near-infrared luminescence emission, which can efficiently avoid the interference of autofluorescence in biological tissues. Photo-luminescent (PL) experiments also reveal that **NIR-1** could be used as a near-infrared ratiometric luminescent sensor for felodipine detection with high selectivity and sensitivity, the low of detection limit (LOD) is 6.39 nM in felodipine detection, which is also performed using real biological samples. In addition, **NIR-1** can be used as a ratiometric thermometer could also be applied in the temperature sensing from 293 K to
Who reads Near-infrared Magnetic Core-shell Nanoparticles Based on Lanthanide Metal-organic Frameworks as a Ratiometric Felodipine Sensing Platform?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Yu-Peng Jiang; Xin-Hui Fang; Qian Wang; Jian-Zhong Huo; Yuan-Yuan Liu; Xin-Rui Wang; Bin Ding
- Publisher
- Springer Science and Business Media LLC
- Published
- 2023
- Language
- EN
- Field
- Chemistry (Physical Sciences)