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Risk assessment of patients with hematologic malignancies who develop fever accompanied by pulmonary infiltrates: A historical cohort study by Marie von Lilienfeld‐Toal; Axel Glasmacher is a Medicine article available to read on EtoBox.

What is Risk assessment of patients with hematologic malignancies who develop fever accompanied by pulmonary infiltrates: A historical cohort study about?

W e read with interest the article by Offidani et al. 1 regarding the risk assessment of patients with hematologic malignancies who develop fever accompanied by pulmonary infiltrates. The authors focus on favorable prognostic parameters that are easily available (low c-reative protein, high albumin, and a favorable trend in the leukocyte count) and claim (rightly in our opinion) that their prognostic model is clinically useful. Patients with 2 or 3 of these factors were reported to have a survival rate of 95%, whereas only 46% of patients with none or only 1 of these factors survived. Clinical parameters such as hypotension or renal failure were not included in the multivariate analysis because they were clearly associated with an adverse prognosis and were found to occur in only a minority of patients. However, we wonder why the authors did not include a measure of patient performance status such as the Karnofsky performance status (KPS) or World Health Organization performance status because this variable is easily available at any time point and may add valuable information. We retrospectively evaluated a cohort of 120 mostly neutropenic patients with pulmonary infiltrates accom

Who reads Risk assessment of patients with hematologic malignancies who develop fever accompanied by pulmonary infiltrates: A historical cohort study?

Author

Marie von Lilienfeld‐Toal; Axel Glasmacher

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)

Published

2005

Language

EN

Field

Medicine (Health Sciences)